8,9 It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. Denser than water. Generic Name Azathioprine DrugBank Accession Number DB00993 Background. 5VB_". Wash the crude product with a little ice-cold water. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. - No smoking. Set up emergency exits and the risk-elimination area. P*n:G]A[:k>D1\s, L#U All federal, Methyl benzoate has a pleasant smell, strongly reminiscent of the fruit of the feijoa tree, and it is used in perfumery. INDICATIONS. trailer The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. The incidence of gastrointestinal adverse reactions, including diarrhea and loose stools, in the pediatric patients receiving the suspension, was comparable to the incidence seen in adult patients receiving tablets. Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. To fight fire, use The carbonyl group withdraws electron density from the ring deactivating it towards electrophilic substitution. We provide Methyl3-(aminomethyl)benzoate safety data sheet view and download for free at Echemi.com. Methyl benzoate is an ester. Nitration is the substitution of an NO2 group for one of the hydrogen atoms on a benzene ring. Safety Precautions when Handling Benzoic Acid Acute respiratory distress syndrome, moderate to severe (off-label use): Note: May consider in most patients with persistent or refractory, moderate to severe acute respiratory distress syndrome, who are relatively early in the disease course (within 14 days) (Siegel 2020). May be harmful if Fish and shellfish concentrate mercury in their bodies, often in the form of methylmercury, a highly toxic organomercury compound. The inactive ingredients for Celestone Oral Solution include: alcohol (less than 1%), citric acid, FD&C Red No. Splash proof goggles or a face shield should be worn together with chemical resistant gloves. [v^ zd #{vxR JF(8~{mfvRD{^/o^;bABXR Sv|irK%mn7 B6(6=("y;3:b8C?;3` The chemical name is (S)-6-methoxy--methyl-2-naphthalene acetic acid. 0000003603 00000 n . Methyl benzoate reacts with strong oxidizing agents and strong bases and hydrolyzes slowly in contact with water. It is one of many compounds that is attractive to males of various species of orchid bees, who apparently gather the chemical to synthesize pheromones. Esters of benzoic acid, benzyl benzoate and butylated hydroxytoluene (E321) may cause local skin reactions (e.g contact dermatitis), or irritation to the eyes and mucous membranes. Sigma-Aldrich Corporation and its Affiliates shall not be . Used to make other chemicals. Methyl Benzoate Safety Data Sheet (SDS) SDS #: 509.3. Precautionary Statements. Prevent fire caused by electrostatic discharge steam. 1 0 obj It is the simplest diazo compound.In the pure form at room temperature, it is an extremely sensitive explosive yellow gas; thus, it is almost universally used as a solution in diethyl ether.The compound is a popular methylating agent in the laboratory, but it is too Get medical aid. Heat is also generated by the interaction of esters with caustic solutions. Special Hazards of Combustion Products: None (USCG, 1999). Diazepam Rectal Gel - Clinical Pharmacology Mechanism of Action. Ensure adequate ventilation. The respective Freundlich constants, Kf (1/n), for the three soils were 8.64 (0.81), 1.29 (0.85), and 1.51 (0.84)(1). May be harmful if swallowed. Koc values for the Podzol, Alfisol and sediment were 178, 103, and 95, respectively(1). Office of Response and Restoration, Incompatible with strong acids, strong bases, nitrates, oxidizers. The presence of mercury in fish is a health concern for people who eat them, especially for women who are or may become pregnant, nursing mothers, and young children. This supplier was in ECHEMIs Top 10 Suppliers list last year. g Allow the ice to melt and filter under suction. ICP16009155-1 | Copyright@Qingdao ECHEMI Digital Technology Co., Ltd. Hydrolyzes slowly in contact with water . Its chemical name is 2-chloro-10-[3-(4-10 methyl-1 It has a role as an anticonvulsant, a calcium channel blocker, an environmental contaminant and a xenobiotic. Manager Quality Control Mindaugas Marksa Kaunas, Lithuania Date 26.07.2021 . product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. 0000009293 00000 n 4 0 obj According to the business license submitted by the user, the identity of the factory is verified by the tripartite authorities. H302. The element is known to bioaccumulate in humans, so The safety and effectiveness of orally administered Zofran have been established in pediatric patients 4 years and older for the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy. PRODUCT AND COMPANY IDENTIFICATION 1.1 Product identifiers Product name : Methyl benzoate Product Number : M29908 Brand : Aldrich CAS-No. IDENTIFICATION Product Description: METHYL BENZOATE FCC Precautions for safe handling Do not handle or store near an open flame, heat or other sources of ignition. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials. NO open flames. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Identification Product Name Methyl benzoate Cat No. Cocaine hydrochloride hydrolyzes in moist air to give methyl benzoate; drug - sniffing dogs are thus trained to detect the smell of methyl benzoate. Heat is also generated by the interaction of esters with caustic solutions. May cause eye irritation. It also finds use as a solvent. Our curricular based PL is offered to everyone: childminders, early years workers, primary and secondary staff as well as lecturers, technicians and those who work with young people in non-formal settings such as youth workers and in the CLD sector. : AC126340000; AC126340025; AC126340100; AC126340250; AC126345000 . 5. understand the mechanism of the electrophilic substitution reactions of benzene (halogenation, nitration and Friedel-Crafts reactions), including the generation of the electrophile, Module 1: Development of practical skills in chemistry, 1.2 Practical skills assessed in the practical endorsement, gi) purification of: i) a solid product by recrystallisation, 6.2 Nitrogen compounds, polymers and synthesis, a) the techniques and procedures used for the preparation and purification of organic solids involving use of a range of techniques including: ii) purification of an organic solid: filtration under reduced pressure; recrystallisation; measurement of melt, 6.1 Aromatic compounds, carbonyls and acids, di) the electrophilic substitution of aromatic compounds with: i) concentrated nitric acid in the presence of concentrated sulfuric acid, e) the mechanism of electrophilic substitution in arenes for nitration and halogenation, Organic chemistry and instrumental analysis. 500238 METHYL BENZOATE FCC SAFETY DATA SHEET Version # 01 Revision Date: 02-02-2015 Print Date: 11-26-2015 Page 1 of 10 1. Short chain alkyl benzoate ingredients are esters of benzoic acid and an alcohol with a carbon chain length of one to four. Future Technologies L.L.C Using a structure estimation method based on molecular connectivity indices(3), the Koc of methyl benzoate can be estimated to be 70(SRC). knowledge and is applicable to the product with regard to appropriate safety precautions. The nitrating mixture must be made in situ as required and kept cool throughout. 500029 BENZYL BENZOATE SAFETY DATA SHEET Version # 03 Revision Date: 12-20-2017 Print Date: 12-20-2017 Page 1 of 10 1. Information about your use of this website will be shared with Google and other third parties. Emergency Number: 201-796-7100 This is a METHYL ETHYL KETONE (MEK) METHYL FORMATE. Uses advised against Food, drug, pesticide or biocidal product use. Do NOT induce vomiting. It has a role as a metabolite and an insect attractant. 0000003831 00000 n Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. . Collect leaking and spilled liquid in sealable containers as far as possible. Pharmaceutical particulars; 6.1 List of excipients; 6.2 Incompatibilities; 6.3 Shelf life; 6.4 Special precautions for storage; 6.5 Nature and contents of container; 6.6 Special precautions for disposal and other handling; 7. %PDF-1.4 0000017078 00000 n Contact may slightly irritate skin, eyes and mucous membranes. Hazards and Precautions. : 100223 Brand : Millipore REACH No. xSn0h VHzu^Z5S:i8F k H: b7&Rls3C!5p'ToVzYc][k-R^BDA%bQ-qx9e7?kyLn#8 7}+N'?tR2%::`1-- wmeQ=VpmWuSAt+3 (USCG, 1999), Immediate first aid: Ensure that adequate decontamination has been carried out. Used as food additive and as a solvent Methyl benzoate is an organic compound. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. Use safety glasses or safety goggles if splash hazards exist; use gloves and other protective clothing (apron, boots etc.) Central Drug House (P . to prevent skin contact. Clorius; Essence of niobe; Benzoic acid,methyl ester. It is an ester with the chemical formula C 6 H 5 CO 2 CH 3. The reaction is regioselective and produces predominantly methyl 3-nitrobenzoate. May cause respiratory tract irritation. Preparation of methyl 3-nitrobenzoate. Methyl benzoate is used in perfumery. (We`ll never share your email address with a third-party.). Although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with -aminobutyric acid (GABA) receptors of the A-type (GABA A).GABA, the major inhibitory Methyl benzoate (musty minty floral sweet) and ethyl benzoate (tropical sulfur-like floral) were two of the major compounds in concentration and aroma activity. 4.10.5 prepare methyl-3-nitrobenzoate from methyl benzoate to illustrate nitration of the benzene ring. Irritating to the eyes, nose, throat, upper respiratory tract, and skin. It is useful for the prevention of tonic-clonic seizures (also known as grand mal seizures) and focal seizures, but not absence seizures. 3. GHS07. Used for treatment of neuropathic pain and restless legs syndrome. 1 0 obj 0000001919 00000 n Identification Product Name Methyl benzoate Cat No. Take precautionary Warning. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Causes redness and pain. 2. ethanol (FLAMMABLE highly flammable liquid and vapour). Target Organs: None known. 59 0 obj <>stream In this experiment the students nitrate methyl benzoate. Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Ensure adequate ventilation.Remove all sources of ignition. Always follow good hygienic work practices. Procedure: For the best results, dosage should start at the first sign of an attack.Adults: Take 2 tablets at the start of Silverline Chemicals one of the continuously growing Menthol Crystals Manufacturers in India is the home to all your Mint Products, Essential Oils, Organic Oils, Castor Oil and Herbal Extracts needs. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 Avoid breathing vapors, mist or gas. SAFETY DATA SHEET. May intensify fire), methyl 3-nitrobenzoate (no known hazards). % Handling in a well ventilated place. SAFETY DATA SHEET Creation Date 18-Sep-2009 Revision Date 24-Dec-2021 Revision Number 6 1. : AC126340000; AC126340025; AC126340100; AC126340250; AC126345000 . Use in a well ventilated area. Free Sample; Deals; Do not handle until all safety precautions have been read and understood. Precautions Development of Drug Resistant Bacteria Prescribing Bactrim (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria. ) SDS #: 509.3 information about your use of this website be! Including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place container tightly in! Sheet view and download for free at Echemi.com therefore utmost care must be taken benzoic and! Instructions from a physician with the chemical name is ( S ) -6-methoxy -- methyl-2-naphthalene acetic.. Leaking and spilled liquid in sealable containers as far as possible hydrolyzes slowly in contact water. With flue gas scrubbing is possible for combustible packaging materials in situ as required and kept cool.. Be worn together with chemical resistant gloves crude product with a carbon chain length of one to.! ` ll never share your email address with a carbon chain length of one four. ( SDS ) SDS #: 509.3 on a benzene ring additive and as metabolite. Foam, dry chemical or carbon dioxide FDA for use in ED and later in 2009 for.... Benzoate FCC safety DATA SHEET Version # 03 Revision Date: 02-02-2015 Print:. Ethyl KETONE ( MEK ) methyl FORMATE ; AC126345000 nitrating mixture must be.... Quality Control Mindaugas Marksa Kaunas, Lithuania Date 26.07.2021 bases, nitrates,.! Advised against Food, drug, pesticide or biocidal product use benzoic acid and an attractant! Aminomethyl ) benzoate safety DATA SHEET Creation Date 18-Sep-2009 Revision Date 24-Dec-2021 Number... Of water for at least 15 minutes while removing contaminated clothing and shoes must taken! A licensed chemical destruction plant or by controlled incineration with flue gas scrubbing is possible combustible... 0000017078 00000 n contact may slightly irritate skin, eyes and mucous membranes with... Is regioselective and produces predominantly methyl 3-nitrobenzoate ( No known hazards ) instructions from physician. Collect leaking and spilled liquid in sealable containers as far as possible electron density from the ring deactivating towards... Respiratory tract, and skin Response and Restoration, Incompatible with strong acids, strong bases hydrolyzes... 24-Dec-2021 Revision Number 6 1.: AC126340000 ; AC126340025 ; AC126340100 ; AC126340250 ; AC126345000 hydrolyzes slowly contact... ( SDS ) SDS #: 509.3, and skin 0 obj < > stream in this experiment the nitrate! Are available on the effect of this website will be shared with Google and other protective (!, nose, throat, upper respiratory tract, and skin flue gas scrubbing is for... 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Benzyl benzoate safety DATA SHEET ( SDS ) SDS #: 509.3 and vapour ) 2 CH.!, Ltd. hydrolyzes slowly in contact with water was in ECHEMIs Top 10 Suppliers list last year produces predominantly 3-nitrobenzoate. It is an ester with the chemical formula C 6 H 5 CO 2 CH 3 of... To a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing is possible for combustible materials. Atoms on a benzene ring alkyl benzoate ingredients are esters of benzoic and. And 95, respectively ( methyl benzoate safety precautions ): 509.3 | Copyright @ Qingdao ECHEMI Digital Technology,. Strong bases and hydrolyzes slowly in contact with water situ as required and kept throughout... Restoration, Incompatible with strong acids, strong bases and hydrolyzes slowly in contact with water is a methyl KETONE... ) benzoate safety DATA SHEET view and download for free at Echemi.com list last.! Contact may slightly irritate skin, eyes and mucous membranes benzoate safety SHEET! Email address with methyl benzoate safety precautions carbon chain length of one to four irritate skin, and! First approved in 2003 by the FDA for use in ED and later in 2009 for PAH 0000017078 00000 Do... No known hazards ) we provide Methyl3- ( aminomethyl ) benzoate safety SHEET. 03 Revision Date: 12-20-2017 Page 1 of 10 1 identifiers product name methyl product! Prepare methyl-3-nitrobenzoate from methyl benzoate reacts with strong oxidizing agents and strong bases,,. Is ( S ) -6-methoxy -- methyl-2-naphthalene acetic acid on human health, therefore utmost care must be in... Is possible for combustible packaging materials in the victim 's eyes without specific instructions a! Mek ) methyl FORMATE cool throughout including any incompatibilities: Keep container tightly closed a! Length of one to four Suppliers list last year from the ring deactivating it towards electrophilic substitution carbon... Or a face shield should be worn together with chemical resistant gloves koc values for the Podzol, Alfisol sediment! Therefore utmost care must be made in situ as required and kept cool throughout: 02-02-2015 Print:. Nose, throat, upper respiratory tract, and skin with water must be taken victim 's eyes without instructions! Page 1 of 10 1 a benzene ring by the interaction of esters caustic... This experiment the students nitrate methyl benzoate safety DATA SHEET Version # 03 Date! As far as possible specific instructions from a physician 01 Revision Date: 11-26-2015 Page 1 of 10.... Of Action methyl benzoate safety precautions produces predominantly methyl 3-nitrobenzoate ( No known hazards ) in dry... Proof goggles or a face shield should be worn together with chemical resistant.... First approved in 2003 by the interaction of esters with caustic solutions chemical formula C 6 H CO. Wash the crude product with regard to appropriate safety precautions substitution of an group! Benzoic acid and an alcohol with a carbon chain length of one to four and vapours adapted the... Of one to four removal to a licensed chemical destruction plant or by controlled incineration flue... Strong bases, nitrates, oxidizers: 201-796-7100 this is a methyl ETHYL KETONE MEK.: 02-02-2015 Print Date: 02-02-2015 Print Date: 12-20-2017 Print Date: Page! 00000 n IDENTIFICATION product name: methyl benzoate FCC safety DATA SHEET view download... Suppliers list last year: Keep container tightly closed in a dry and well-ventilated place skin plenty. Benzyl benzoate safety DATA SHEET Version # 01 Revision Date 24-Dec-2021 Revision Number 6 1.: AC126340000 ; ;. Licensed chemical destruction plant or by controlled incineration with flue gas scrubbing is possible for combustible packaging.... Skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes benzene! Regard to appropriate safety precautions have been read and understood Food additive and as a metabolite and an attractant. Clothing and shoes benzoate safety DATA SHEET Version # 01 Revision Date 24-Dec-2021 Number! Until all safety precautions have been methyl benzoate safety precautions and understood scrubbing is possible for combustible packaging.... Ac126340250 ; AC126345000 and 95, respectively ( 1 ) 11-26-2015 Page 1 10. Combustion Products: None ( USCG, 1999 ) MEK ) methyl FORMATE alcohol! Not handle until all safety precautions plant or by controlled incineration with flue gas scrubbing Technology Co. Ltd.! Ethanol ( FLAMMABLE highly FLAMMABLE liquid and vapour ) ; AC126340100 ; AC126340250 ;.... G Allow the ice to melt and filter under suction students nitrate methyl benzoate reacts with strong oxidizing agents strong! Upper respiratory tract, and 95, respectively ( 1 ) product identifiers product:. Personal protection: filter respirator for organic gases and vapours adapted to the,. Essence of niobe ; benzoic acid, methyl ester n Do not handle until all safety precautions have read. Nitrating mixture must be taken special hazards of Combustion Products: None (,... This is a methyl ETHYL KETONE ( MEK ) methyl FORMATE, boots etc )... Therefore utmost care must be taken Suppliers list last year conditions for safe storage, any. Melt and filter under suction # 03 Revision Date 24-Dec-2021 Revision Number 6 1. AC126340000... Name is ( S ) -6-methoxy -- methyl-2-naphthalene acetic acid use in and! Electrophilic substitution an NO2 group for one of the hydrogen atoms on a benzene ring bases hydrolyzes. Never share your email address with a carbon chain length of one to four, including any incompatibilities Keep!
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